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Вопрос 1
A 34-year-old man presents with fever (38°C), headache, and myalgia 7 days after visiting a forest area. After 5 days, his condition improves, but one week later he develops high fever, neck stiffness, and hand tremor.What is the most likely diagnosis?
Варианты ответов
- Influenza
- Lyme disease
- Tick-borne encephalitis
- Meningococcal meningitis
- Virral hemorragic fever
Вопрос 2
A patient with TBE develops central nervous system involvement. Which mechanism is most characteristic?
Варианты ответов
- Viral invasion via bloodstream
- Immune complex-mediated vascular damage
- Direct neurotropism of the virus
- Toxic effect of endotoxine) Delayed-type hypersensitivity reaction
Вопрос 3
A patient with TBE presents with severe headache, photophobia, and neck stiffness without focal neurological deficits.Which clinical form is most likely?
Варианты ответов
- a) Meningeal form
- b) Meningoencephalitic form
- c) Poliomyelitic form
- e) Abortive form
Вопрос 4
A patient is admitted with fever and neurological symptoms after a tick bite. Cerebrospinal fluid shows lymphocytic pleocytosis.Which condition should be excluded first?
Варианты ответов
- a) Brucellosis
- b) Lyme disease (neuroborreliosis)
- c) Salmonellosis
- d) Diphtheria
- e) Malaria
Вопрос 5
Which method is most informative for confirming TBE during the second phase of the disease?
Варианты ответов
- a) Complete blood count
- b) Bacteriological culture of CSF
- c) Serology (IgM antibodies to TBEV)
- d) Blood smear microscopy
- e) Biochemical blood test
Вопрос 6
A patient is diagnosed with TBE. What is the most likely route of transmission?
Варианты ответов
- a) Airborne +Vector-borne (tick bite)
- b) Contact transmission
- d) Sexual transmission +Vector-borne (tick bite)
- c) Vector-borne (tick bite)
- e) Parenteral transmission
Вопрос 7
Which feature is most characteristic of TBE and helps distinguish it from other viral infections?
Варианты ответов
- a) Gradual onset
- b) Biphasic course
- c) Presence of skin rash
- d) Severe cough
- e) Diarrhea
Вопрос 8
A patient with TBE develops flaccid paresis of the upper limbs. What is the most likely complication?
Варианты ответов
- a) Peripheral nerve involvement
- b) Poliomyelitis-like form
- c) Central nerve involvement
- d) Hepatitis
- e) Nephritis
Вопрос 9
A patient with confirmed TBE is hospitalized. What is the main treatment approach?
Варианты ответов
- a) Antibiotic therapy
- b) Specific antiviral therapy
- c) Supportive and symptomatic treatment
- d) Antifungal therapy
Вопрос 10
Which preventive measure is most effective in endemic regions?
Варианты ответов
- a) Antibiotic prophylaxis after tick bite
- b) Vaccination
- c) Use of antiseptics
- d) Immunoglobulin for all contact
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