Intestinal infections
Список вопросов теста
Вопрос 1
A 24-year-old male presents with continuous fever for 10 days, relative bradycardia, and rose spots on the abdomen.
Lab: Widal test: TO 1:320, TH 1:320; Blood culture: Salmonella Typhi isolated.
Question: What is the most likely stage of the disease?
Варианты ответов
- First week
- Convalescence
- Third week
- Second week
Вопрос 2
Which disease may closely resemble typhoid fever during early stages but can be distinguished by relative lymphocytosis?
Варианты ответов
- Brucellosis
- Malaria
- Leptospirosis
- Shigellosis
- Viral hepatitis A
Вопрос 3
A 5-year-old child has fever, tenesmus, and bloody-mucous stools.
Stool microscopy: Many WBCs, RBCs, no protozoa.
Culture: Non-lactose fermenter on MacConkey, oxidase-negative.
Question: Which is the causative agent?
Варианты ответов
- Salmonella enteritidis
- Vibrio cholerae
- Shigella flexneri
- E. coli (ETEC)
- Campylobacter jejuni
Вопрос 4
Which feature helps differentiate shigellosis from amoebic dysentery?
Варианты ответов
- Mucus in stool
- Presence of cysts in stool
- Presence of trophozoites with ingested RBCs
- Fever and tenesmus
- Bloody diarrhea
Вопрос 5
After eating raw eggs, several people develop nausea, vomiting, and diarrhea within 8 hours.
Stool culture: Salmonella enteritidis.
Question: What is the mechanism of infection?
Варианты ответов
- Toxin-mediated gastroenteritis
- Invasive infection via macrophages
- Bacteremia
- Spore formation
- Latent colonization
Вопрос 6
A 30-year-old woman presents with diplopia, dysphagia, and descending paralysis after eating home-canned mushrooms.
Lab: Mouse bioassay positive for botulinum toxin.
Question: What is the key mechanism?
Варианты ответов
- Inhibition of acetylcholine release
- Demyelination of peripheral nerves
- Destruction of neuromuscular junction
- Activation of GABAergic neurons
- Inhibition of acetylcholinesterase
Вопрос 7
A 12-year-old child presents with jaundice, dark urine, elevated ALT/AST (>1000 IU/L).
Serology: Anti-HAV IgM positive.
Question: What does this indicate?
Варианты ответов
- Past infection
- Current acute infection
- Chronic infection
- Vaccinated status
- Co-infection with HBV
Вопрос 8
A patient’s lab results:
HBsAg (+), HBeAg (+), Anti-HBc IgM (+), ALT high.
Question: Interpretation?
Варианты ответов
- Acute infection, high infectivity
- Carrier state
- Chronic infection, low infectivity
- Recovery phase
- Vaccinated status
Вопрос 9
ELISA anti-HCV positive, PCR HCV-RNA positive.
Question: What does this indicate?
Варианты ответов
- Past resolved infection
- False positive
- Active ongoing infection
- Vaccination
- Window period
Вопрос 10
A patient with acute hepatitis has both HBsAg and anti-HDV IgM.
Question: What is the correct interpretation?
Варианты ответов
- HBV infection only
- Chronic HBV with HDV superinfection
- Acute HBV + HDV co-infection
- Resolved HBV infection
- Vaccine-induced immunity
Вопрос 11
A 26-year-old teacher presents with abrupt onset fever, myalgia, and dry cough.
Lab: Nasopharyngeal swab positive for Influenza A RNA.
Question: Best initial antiviral therapy?
Варианты ответов
- Penicillin
- Oseltamivir
- Azithromycin
- Acyclovir
- Ribavirin
Вопрос 12
A 2-year-old child presents with barking cough and inspiratory stridor.
X-ray: Steeple sign.
Diagnosis: Croup.
Question: Most probable etiologic agent?
Варианты ответов
- Parainfluenza virus type 1
- RSV
- Adenovirus
- Influenza B
- Rhinovirus
Вопрос 13
A 45-year-old male with fever, cough, and loss of smell.
Lab: RT-PCR SARS-CoV-2 positive. CRP 60 mg/L, lymphopenia.
Question: Which marker correlates with severe disease?
Варианты ответов
- Lymphocytosis
- Elevated CRP and D-dimer
- Normal ferritin
- Decreased LDH
- High platelet count
Вопрос 14
ELISA test positive for HIV antibodies.
Question: Which confirmatory test is recommended?
Варианты ответов
- PCR for RNA
- Western blot
- VDRL
- HBsAg
- Mantoux test
Вопрос 15
A patient with recurrent oral candidiasis, CD4 = 180/μL.
Question: What is the stage of HIV infection?
Варианты ответов
- a) Acute HIV infection
- b) Asymptomatic stage
- c) AIDS stage
- d) Seroconversion illness
- e) Early latent
Вопрос 16
A 34-year-old man with jaundice, ALT 800 IU/L, ALP 120 IU/L, bilirubin 150 μmol/L. No history of alcohol use.
Serology: HBsAg negative, anti-HAV IgM positive.
Question: Likely diagnosis?
Варианты ответов
- a) Obstructive jaundice
- b) Alcoholic hepatitis
- c) Viral hepatitis A
- d) Drug-induced hepatitis
- e) Hemolytic jaundice


