Infectious diseases 7th semester 1st module
Список вопросов теста
Вопрос 1
The discovery of new antibiotics is important to be ahead of drug resistance. Which of the following classes of antibiotics, latest to be discovered in the last 15 years?
Варианты ответов
- Macrolides
- Glycopepetides
- Quinolones
- Lipopeptides
- Oxazolidiones
Вопрос 2
Which of the following infections should you use handwashing with soap and water?
Варианты ответов
- Methicillin-resistant Staphylococcus aureus
- Pneumonia
- Clostridium difficile
- Hepatitis A virus
Вопрос 3
The ability of the immune system to recognize selfantigens versus non-self-antigen is an example of:
Варианты ответов
- Specific immunity
- Humoral immunity
- Cell mediated immunity
- Tolerance
Вопрос 4
The germ that causes typhoid fever can enter (and remain) in a carrier state because:
Варианты ответов
- some people are genetically unable to make the antibody that recognizes it
- it lodges in tissues that are not supplied with blood or lymph
- it hides inside cells in special vesicles
- it is a “slow virus”
- it can cross the blood-brain barrier
Вопрос 5
The course of antimicrobial therapy of typhoid fever is carried out
Варианты ответов
- The course of antimicrobial therapy of typhoid fever is carried out
- up to 10 days of normal temperature
- within 14 days
- Up to 7 days of normal temperature
Вопрос 6
The ED reports 3 cases of cramping, abdominal pain, and
diarrhea within a 24-hour period. All persons are from the same
community, and onset of symptoms was within 12 to 36 hours of
a picnic they all attended. The IP suspects which of the following
foodborne illnesses:
Варианты ответов
- Salmonella
- Hepatitis A
- Staphylococcus aureus
- Clostridium perfringens
Вопрос 7
An 18-month-old boy presented with 4 days of sudden onset, severe watery diarrhea, after 2 days of being nonspecifically unwell. He was passing stool approximately 15 times/day. He had vomited for one day, but this then stopped. There was no blood in the stool. He was also noted to have a dry cough and appeared to have coryzal symptoms. He had not had a wet nappy for 24 hours. He had stopped breast feeding at 12 months old. On examination, he was markedly dehydrated, with a tempera ture of 38.5 °C and a tachycardia. He required aggressive fluid resuscitation. In addition to intravenous fluids or oral rehydration solutions, what agent would improve his outcome?
Варианты ответов
- Ascorbic acid
- Cholecalciferol
- Magnesium
- Thiamine
- Zinc
Вопрос 8
The absolute indication for parenteral rehydration therapy is
Варианты ответов
- dehydration of the 2nd degree;
- vomiting
- febrile temperature
- diarrhea
Вопрос 9
The presence of bloody diarrhea in salmonellosis requires differential diagnosis with:
Варианты ответов
- gastric ulcer
- irritable bowel syndrome
- shigellosis
- duodenal ulcer
Вопрос 10
The pathogenesis of Escherichiosis caused by enteroadhesive escherichia is based on:
Варианты ответов
- attachment to epithelial cells, stimulation of mucus production, formation of a thick mucous layer
- destruction of endothelial cells of small blood vessels of the intestinal wall of the proximal colon
- increased activity of adenylate cyclase and guanylate cyclase by enterotoxins, increased cAMP synthesis
- the development of an inflammatory reaction, increased intake of endotoxins into the blood, damage to the mucous membrane of the colon
Вопрос 11
Salmonellosis differs from escherichiosis in the presence of:
Варианты ответов
- intoxication
- abundant stool with a greenish tinge
- dehydration
- abdominal pain
Вопрос 12
A 25-year-old man and his fiancé also aged 25 is
hitch-hiking to Latin America. They are enquiring
about the typhoid vaccine. Which of the following
statements is CORRECT?
Варианты ответов
- Typhoid vaccine is not really necessary for travel to endemic areas provided food hygiene is observed
- Multi-drug resistant strains are prevalent in Latin America
- Typhoid vaccine is unsafe for immune-compromised individuals
- Primary protection consists of one 0.5 ml intramuscular injection
- The Vi capsular polysaccharide typhoid vaccine is NOT licenced in Singapore
Вопрос 13
At the reception of the district pediatrician, a mother with a child aged 10 weeks. The eldest child in the family (5 years old) suffered a severe form of rotavirus infection 2 years ago.The mother asks the pediatrician what can be most effective for the prevention of rotavirus infection for a younger child?
Варианты ответов
- Antibiotic therapy
- Get vaccinated against rotavirus infection
- To carry out immunotherapy
Вопрос 14
An 11-month-old boy complains on high fever, malaise, irritability and poor feeding, macular rash , number of perioral lesions, but no lesions visible inside the mouth and on the soles.of his feet. He had had his vaccinations as per the schedule for his age. He had been born at full term and was meeting his developmental milestones. He lived at home with two older siblings.
What is the most likely pathogen?
Варианты ответов
- Adenovirus
- Coxsackievirus A6
- Echovirus
- Herpes simplex virus
Вопрос 15
A 32 year old male has traveled to Brazil for 3 months. During that period he went to a traditional sea food restaurant after a while he noticed cramps and has developed severe diarrhea. What is the diagnosis?
Варианты ответов
- Shigellosis
- Food toxic infection
- Cholera
- Enteroviral infection
Вопрос 16
Duration of excretion of enteroviruses with feces
Варианты ответов
- 7 days
- 5-6 weeks
- 3-6 months
- 24 hours
Вопрос 17
Characteristic symptoms of herpangina are:
Варианты ответов
- small whitish spots on the buccal mucosa
- small papules and vesicles on palatine arches, tonsils, palate, uvulae
- aphthae and small erosions on the mucous membranes of the cheeks, lips, tongue, Palatine arches
- located the subepithelial lymphoid festering education
Вопрос 18
What is the mechanism of action of botulinum toxin?
Варианты ответов
- Myopathy caused by inflammatory processes.
- Parasympathetic reaction from the massive stimulation of cholinergic receptors
- Paralysis caused by demyelination
- Skeletal muscle paralysis due to dysregulation of acetylcholine
Вопрос 19
Specify the dose of type B anti-botulinum serum :
Варианты ответов
- 1000U
- 2000U
- 5000U
- 10000U
- 15000U
Вопрос 20
The nature and duration of vomiting in rotavirus infection can be described as follows:
Варианты ответов
- Persistent vomiting, occurring in the context of a diarrheal condition
- Brief episodes of vomiting lasting for a short period (1-2 days), occurring in the context of a feverish state
- The occurrence of vomiting is not a typical symptom
- Vomiting of varying frequency, often preceding the onset of diarrhea
- Vomiting of varying frequency, occurring after the resolution of diarrhea


